annette – menchelab

Posted on by

AutoCore

In a project that is currently under review for publication, we developed a network-based framework for integrating all currently known monogenic immune defects and their molecular interactions. We identify the AutoCore, that is, the set of genes and their molecular interactions that are essential for immune homeostasis. A brief overview of the project can be found on a dedicated website. We implemented a webapp where the AutoCore can be interactively explored. The code is available on github.

Posted on by

Bioprofiling.jl

We have developed a series of tools for analyzing microscopy images from high-content imaging screens. In 2021, we published a dedicated package for the high-performance programming language Julia. The package allows for performing robust multidimensional profiling and comes with data structures and helper functions especially designed for high-content imaging-based morphological profiling. You can access the package from the Julia repository or from github.

Posted on by

MultiOme Explorer

Rare genetic diseases affect various levels of biological organization between the genome and the whole organism. You can find a general introduction on this topic here. In 2021, we published a comprehensive analysis of 3,771 rare diseases and a their connection patterns on a multiplex network consisting of over 20 million gene relationships that are organized into 46 network layers spanning six major biological scales between genotype and phenotype. You can explore the results and investigate the connections among genes associated to a disease of interest in our interactive webapp. The code for all analyses presented in the paper can be found on our github page. The repository also contains a walk-through guide for reproducing the figures and analyses.

Posted on by

CartoGraph Network Visualizations

Networks offer a powerful visual representation of complex systems. In 2022, we published CartoGraphs, a framework for generating a diverse set of network layouts for highlighting and visually inspecting chosen characteristics of a network. The resulting visualizations are interpretable and can be used to explore complex datasets, such as large-scale biological networks. A general introduction to CartoGraphs can be found on a dedicated website and a research briefing. Our webapp allows users to generate their own CartoGraphs, all source code and detailed instructions are available on github.

Posted on by

Virtual Reality Platform VRNetzer

Our team is pioneering the usage of Virtual Reality technology for interactively exploring large networks and other complex datasets. You can find a series of introductory videos on a dedicated website. In 2021 we published our first proof-of-concept of a VR platform for biological network analysis, you can read the paper here. Since then, we have been constantly updating and extending our platform. Detailed instructions and tutorials can be found on our github page.

Posted on by

Death or the Absolute Now

We presented a Virtual Reality art work at the exhibition Death or the Absolute Now at the MuseumsQuartier in Vienna. The exhibition featured art works offering different perspectives, interpretations and reflections on the concept of time and death.

Death or the Absolute Now (2018)
art4art.at

Posted on by

Bodyscan

Our Virtual Reality platform was featured at the Bodyscan exhibition in Munich. The exhibition organized by the Eres foundation featured more than 50 pieces exploring the human anatomy, ranging from historical models to contemporary works of art.

Bodyscan (2019)
eres-stiftung.de

Posted on by

GLOBART academy

We showed our Virtual Reality platform during the GLOBART academy festival at the Essl museum in Klosterneuburg. GLOBART invited innovators, artist, activists and scientists to present their work, exchange ideas, and play an active part in transforming the museum into a lively space for creating the future.

Future Innovator Summit (2019)
globart-academy.at

Posted on by

Vienna Ball of Sciences

Our team presented our Virtual Reality platform during the Vienna ball of sciences 2020. The ball represents Vienna’s science and research community in its excellence and diversity. Typical elements of a Viennese Ball are combined with contributions from Vienna’s universities.

Vienna Ball of Sciences (2020)
wissenschaftsball.at

Posted on by

Future Innovator Summit

Jörg took part at the Future Innovators Summit within the Ars Electronica Art Thinking School program. Future Innovators from different cultures and backgrounds and from different fields – such as artists, designers, scientists, engineers, entrepreneurs, social activists and philosophers – explored new ways of collective brainstorming on the crucial questions for humanity, and to create future scenarios.

Future Innovator Summit (2019)
ars.electronica.art