The regulatory network architecture of cardiometabolic diseases

Complex disease definitions often represent descriptive umbrella terms of symptoms rather than mechanistic entities. In this brief News & Views article we highlight a new study that shows how network-based approaches can help identify the mechanisms that link genes, cells, tissues and organs in cardiovascular diseases. We discuss how network medicine approaches can help accelerate the development of early and individualized diagnostics and therapeutics in the coming era of precision medicine.

NATURE GENETICS (2022)
doi.org/10.1038/s41588-021-00994-w [pdf]